As a Church of Ireland venue of worship, they are a full member of the Anglican Communion. Their aim is to be at the heart of the community, developing commitment, outreach, worship, and showing Christian love, while also welcoming everyone, regardless of colour, creed, or class. The Apostles’ Creed and the Nicene Creed summarise their beliefs.

Their church was meant to be a part of the new town of Enniskillen, which was constructed in the years following 1611 on King James the First of England’s orders. The original church building was probably constructed about 1627. Richard Pokrich, one of the founders, had a son called William who, unfortunately for Richard, was the first person to be buried at the cemetery in 1628. William’s gravestone has been integrated into the cathedral’s wall, where it can be seen by everyone.

Although little of the original church remains, a part of it was incorporated into the present one and may be seen above the main entrance door, where there is a small, antique three-light lattice window and a carved stone dated 1637, as well as the Agnus Dei (Lamb of God).